Azathioprine

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meme nony
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Azathioprine

Unread post by meme nony »

Azathioprine

Azathioprine is metabolised to the active compound mercaptopurine, a purine analogue that inhibits purine synthesis. A thiopurine methyltransferase (TPMT) test may be needed to look for individuals prone to azathioprine toxicity.

Adverse effects include
•bone marrow depression
•nausea/vomiting
•pancreatitis

A significant interaction may occur with allopurinol and hence lower doses of azathioprine should be used.
ammar tajedinn
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Re: Azathioprine

Unread post by ammar tajedinn »

thnkx
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